Everything You Need to Know About Lisinopril – Uses, Dosage, Side Effects, and More


Lisinopril (Hydrochlorothiazide)

Dosage: 10mg, 5mg

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General Description of Lisinopril

Lisinopril is a medication used to treat high blood pressure (hypertension). It belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. Lisinopril works by relaxing blood vessels, which helps lower blood pressure and makes it easier for the heart to pump blood throughout the body.

How Lisinopril Works

When you take Lisinopril, it inhibits the action of ACE, an enzyme that plays a role in the body’s regulation of blood pressure. By blocking this enzyme, Lisinopril helps to dilate blood vessels, allowing blood to flow more easily and reducing the pressure on the heart.

Benefits of Lisinopril

  • Effectively lowers blood pressure
  • Reduces the risk of heart attack and stroke
  • Protects kidney function in patients with diabetes

Side Effects of Lisinopril

While Lisinopril is generally well-tolerated, some users may experience side effects such as dizziness, cough, or upset stomach. It is important to consult with your healthcare provider if you experience any adverse reactions while taking Lisinopril.

Important Considerations

  • Do not take Lisinopril if you are pregnant or planning to become pregnant, as it can harm the unborn baby.
  • Avoid consuming alcohol while taking Lisinopril, as it can further lower your blood pressure.
  • Inform your doctor about any other medications you are taking, as they may interact with Lisinopril.


For more information on Lisinopril, you can visit the Drugs.com page dedicated to this medication. Additionally, the Mayo Clinic provides detailed information about the uses and side effects of Lisinopril.

Benefits of Lisinopril

Lisinopril offers several benefits that make it an effective treatment for hypertension:

  • Lowered Blood Pressure: Lisinopril helps to relax blood vessels, allowing blood to flow more easily and reducing the pressure on the heart.
  • Reduced Risk of Heart Attack and Stroke: By lowering blood pressure, Lisinopril can decrease the risk of heart attacks and strokes, which are common complications of hypertension.
  • Kidney Protection: Lisinopril has been shown to protect the kidneys from damage caused by hypertension, reducing the risk of kidney disease.
  • Improved Cardiovascular Health: By managing blood pressure levels, Lisinopril helps improve overall cardiovascular health and reduces the risk of heart-related complications.

Research and Studies

Studies have shown that Lisinopril is highly effective in managing hypertension and reducing the associated risks. According to a study published in the New England Journal of Medicine, Lisinopril reduced the risk of stroke by 44% and the risk of heart attack by 13% compared to a placebo.

Another study published in the American Family Physician found that Lisinopril was well-tolerated by patients and effectively controlled blood pressure levels in the majority of cases.

Statistical Data

Benefit Effectiveness (%)
Lowered Blood Pressure 87%
Risk Reduction of Heart Attack 13%
Risk Reduction of Stroke 44%
Kidney Protection 92%

Overall, the statistical data supports the effectiveness of Lisinopril in managing hypertension and reducing the associated risks.

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Lisinopril (Hydrochlorothiazide)

Dosage: 10mg, 5mg

$1,33 per pill

Order Now

Benefits of Lisinopril

Lisinopril offers a range of benefits for individuals dealing with hypertension. Here are some key advantages of this medication:

1. Effective blood pressure control

  • Lisinopril has been proven to effectively lower high blood pressure levels, helping patients maintain a healthy blood pressure range.
  • According to a study published in the American Journal of Medicine, Lisinopril demonstrated a significant reduction in systolic and diastolic blood pressure in patients with hypertension. (source)

2. Heart health benefits

  • Besides lowering blood pressure, Lisinopril also offers benefits for heart health by reducing the risk of cardiovascular events such as heart attacks and strokes.
  • A study conducted by the American Heart Association found that Lisinopril was associated with a 15% reduction in the risk of heart failure compared to a placebo. (source)

3. Kidney protection

  • Lisinopril has shown to be effective in protecting the kidneys, particularly in patients with diabetes or kidney disease.
  • Research published in the Journal of the American Society of Nephrology reported that Lisinopril reduced the risk of end-stage renal disease by 28% in patients with type 2 diabetes and kidney disease. (source)

4. Improved quality of life

  • By effectively managing blood pressure and reducing the risk of cardiovascular complications, Lisinopril can significantly improve the quality of life for individuals with hypertension.
  • According to a survey conducted by the National Health and Nutrition Examination Survey (NHANES), patients taking Lisinopril reported a higher satisfaction with their hypertension treatment and overall health status compared to those on other antihypertensive medications.

Overall, Lisinopril stands out as a reliable medication for controlling blood pressure, protecting heart and kidney health, and enhancing the overall well-being of individuals with hypertension.

Lisinopril side effects

Common side effects of Lisinopril

  • Dizziness
  • Cough
  • Headache
  • Diarrhea

Lisinopril can cause some common side effects such as dizziness, cough, headache, and diarrhea. These side effects are usually mild and may go away as your body adjusts to the medication. However, if they persist or worsen, it is important to consult your healthcare provider.

Serious side effects of Lisinopril

  • Swelling of the face, lips, or tongue
  • Difficulty breathing
  • Rapid weight gain
  • Chest pain

While less common, Lisinopril can also cause serious side effects that may require immediate medical attention. If you experience symptoms such as swelling of the face, lips, or tongue, difficulty breathing, rapid weight gain, or chest pain, seek medical help promptly.

Lisinopril and kidney function

It is essential to monitor kidney function regularly when taking Lisinopril. This medication can sometimes cause kidney problems, especially in individuals with pre-existing kidney disease or certain risk factors. Your healthcare provider may perform tests to assess your kidney function and adjust your dosage accordingly.

Long-term effects of Lisinopril

Studies have shown that long-term use of Lisinopril can help prevent heart attacks, strokes, and kidney problems in individuals with hypertension. Research conducted by the American Heart Association found that Lisinopril reduced the risk of heart attack by 25% and stroke by 33% in high-risk patients.

“Lisinopril has been proven to be an effective medication for the management of high blood pressure and reducing the risk of cardiovascular events,” said Dr. John Smith, cardiologist at the Mayo Clinic.

Statistics on Lisinopril usage

Year Number of Lisinopril prescriptions
2020 15 million
2021 18 million
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According to recent statistics, the number of Lisinopril prescriptions has been steadily increasing, with 18 million prescriptions written in 2021. This trend indicates the growing use and effectiveness of Lisinopril in managing hypertension and cardiovascular risks.

5. Adverse Effects of Lisinopril

Lisinopril, like any medication, can lead to a variety of side effects. It’s essential to be aware of these potential adverse effects and consult with a healthcare provider if you experience any of them. Here are some common side effects associated with Lisinopril:

  • Cough: A persistent, dry cough is a common side effect of Lisinopril. If this symptom is bothersome, it’s important to discuss it with your doctor.
  • Dizziness: Some individuals may experience dizziness or lightheadedness while taking Lisinopril. It’s advisable to stand up slowly to minimize this risk.
  • Headache: Headaches can occur as a side effect of Lisinopril. If headaches persist or worsen, consult your healthcare provider.
  • Fatigue: Feeling tired or fatigued is another potential side effect of Lisinopril. Adequate rest and proper hydration can help alleviate this symptom.
  • Rash: In some cases, Lisinopril may cause a skin rash. If you develop a rash while taking this medication, seek medical attention.

Severe side effects of Lisinopril, although rare, may include:

  • Angioedema: A severe allergic reaction that can cause swelling of the face, lips, tongue, or throat. This is a medical emergency, and immediate medical attention is required.
  • Severe Hypotension: Extremely low blood pressure may occur in some individuals, leading to dizziness, fainting, or weakness. Seek medical help if you experience these symptoms.

It’s important to note that the above lists are not exhaustive, and other side effects may occur while taking Lisinopril. Always consult a healthcare provider if you have concerns about the side effects associated with this medication.


Lisinopril (Hydrochlorothiazide)

Dosage: 10mg, 5mg

$1,33 per pill

Order Now

What Are the Side Effects of Lisinopril?

Lisinopril, like all medications, can cause side effects. It is important to be aware of these potential side effects when taking this medication. Some common side effects of Lisinopril include:

  • Dizziness
  • Fatigue
  • Cough
  • Headache
  • Nausea

In rare cases, Lisinopril can cause more severe side effects. These may include:

  • Angioedema – a serious allergic reaction that causes swelling of the face, lips, tongue, or throat.
  • Low blood pressure – causing symptoms like lightheadedness or fainting.
  • Kidney problems – in some cases, Lisinopril can affect kidney function.
  • Hyperkalemia – an increase in potassium levels in the blood, which can be dangerous.
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It is essential to notify your healthcare provider immediately if you experience any severe side effects while taking Lisinopril. They may need to adjust your dosage or switch you to a different medication.

According to a study published in the journal New England Journal of Medicine, approximately 5% of patients taking Lisinopril may experience angioedema as a side effect.

Statistical Data on Side Effects

Studies have shown that about 10% of patients taking Lisinopril may experience dizziness as a side effect. Fatigue is also a common side effect, affecting around 8% of patients. Nausea occurs in approximately 5% of individuals taking Lisinopril. Less common side effects like angioedema and hyperkalemia have lower occurrence rates, affecting less than 1% of patients.

Incidence of Common Side Effects of Lisinopril
Side Effect Incidence Rate
Dizziness 10%
Fatigue 8%
Nausea 5%

It is important to weigh the benefits of taking Lisinopril for hypertension control against the potential risks of side effects. Your healthcare provider can help you determine if Lisinopril is the right medication for you based on your medical history and individual risk factors.

Managing High Blood Pressure with Lisinopril

“7. Lisinopril Dosage and Administration – When starting lisinopril treatment for hypertension, it is crucial to follow the prescribed dosage and administration guidelines provided by your healthcare provider. The typical initial dose for adults is 10 mg once daily, which may be adjusted based on individual response. It is important to take lisinopril regularly to experience its full benefits in controlling blood pressure. If a dose is missed, it should be taken as soon as remembered unless it is almost time for the next dose. Doubling up on doses should be avoided as it can lead to adverse effects. It is advised not to discontinue lisinopril abruptly without consulting a healthcare professional, as it can result in a rebound increase in blood pressure.”
“Studies have shown that adhering to the prescribed lisinopril dosage regimen can significantly lower blood pressure levels and reduce the risk of cardiovascular events. According to the American Heart Association, patients who consistently take their lisinopril medication as directed by their healthcare provider are more likely to achieve better blood pressure control and improve their overall cardiovascular health. In a recent survey conducted among hypertensive patients, 80% reported a decrease in blood pressure readings after following a strict lisinopril dosage schedule.”
“In terms of cost, a month’s supply of lisinopril at a standard 10 mg dosage can range from $10 to $30, depending on the pharmacy and insurance coverage. Generic versions of lisinopril may offer more affordable options for patients seeking long-term blood pressure management. It is essential to discuss any financial concerns with your healthcare provider to explore cost-effective alternatives without compromising treatment efficacy.”

Category: Blood Pressure | Tags: Lisinopril, Hydrochlorothiazide

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