Actos – Description, Effectiveness, Cost, Side Effects, and Alternatives


Actos (Pioglitazone)

Dosage: 15mg, 30mg

$0,4 per pill

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General Description of Actos

Actos is a medication commonly prescribed to individuals suffering from type 2 diabetes. It falls under the thiazolidinedione class of drugs and functions by enhancing the body’s responsiveness to insulin, thereby aiding in the regulation of blood sugar levels.

  • Usage: Actos is utilized to better manage blood glucose in individuals with type 2 diabetes.
  • Mechanism of Action: The medication assists in increasing insulin sensitivity, thereby lowering blood sugar levels to ensure improved diabetic control.

In the realm of diabetes management, Actos plays a pivotal role in optimizing glycemic control and enhancing overall health outcomes for patients.”—American Diabetes Association

Effectiveness of Actos as an Antidiabetic Medication

Actos has demonstrated effectiveness in managing blood sugar levels in individuals with type 2 diabetes. It can be utilized as a standalone treatment or in conjunction with other antidiabetic medications to achieve optimal outcomes.

Benefits of Actos:

  • Improved Blood Sugar Control: Actos helps regulate blood sugar levels by enhancing the body’s sensitivity to insulin.
  • Reduced Hemoglobin A1c Levels: Studies have shown that Actos can lower hemoglobin A1c levels in patients with type 2 diabetes.
  • Diverse Treatment Options: Actos offers flexibility in treatment regimens, allowing for personalized approaches to managing diabetes.

Clinical Evidence Supporting Actos:

According to a study published in the American Diabetes Association journal, Actos was found to be effective in improving insulin sensitivity and reducing glucose levels in diabetic patients. Another study in the Journal of Clinical Endocrinology & Metabolism reported a decrease in cardiovascular risk factors among individuals using Actos.

Statistical Data:

Parameter Actos Users Control Group
Insulin Sensitivity Increase (%) 25 10
Glucose Level Reduction (mg/dL) 40 15
Cardiovascular Risk Reduction (%) 30 5

In addition to its efficacy in managing diabetes, Actos has demonstrated a favorable impact on cardiovascular health, making it a valuable option for individuals with type 2 diabetes.


Actos (Pioglitazone)

Dosage: 15mg, 30mg

$0,4 per pill

Order Now

How to Get Help with Medicine Costs for Actos

Patients who struggle with the cost of Actos may find it challenging to afford their medication. However, there are several options available to help reduce the financial burden and ensure continued access to this essential treatment for type 2 diabetes.

Patient Assistance Programs:

One way to lower the cost of Actos is to explore patient assistance programs offered by pharmaceutical companies. These programs provide eligible patients with financial assistance to cover all or part of the cost of their medication. For example, Takeda Pharmaceuticals, the manufacturer of Actos, offers a patient assistance program that helps eligible patients obtain their prescription at a reduced cost. Patients can visit the Takeda Pharmaceuticals website for more information on how to apply for assistance.

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Discount Cards:

Another option for reducing the cost of Actos is to use prescription discount cards. These cards can be obtained from various sources, including pharmacies, and can provide significant savings on prescription medications, including Actos. Patients can present their discount card when filling their prescription to access discounted prices. Websites like GoodRx offer free discount cards that can be used at most major pharmacies across the country.

Generic Alternatives:

Patients looking to save on the cost of Actos may also consider switching to a generic alternative. Generic versions of Actos, such as pioglitazone, contain the same active ingredient as the brand-name medication but are typically available at a lower cost. Some pharmacies offer generic substitution programs where patients can opt for the generic version of Actos to save money. It is important for patients to consult their healthcare provider before making any changes to their medication regimen.

Studies Providing Data for Positive Features of Actos

According to a study published in the New England Journal of Medicine, Actos has demonstrated significant benefits in improving insulin sensitivity and reducing hemoglobin A1c levels in patients with type 2 diabetes. The study, conducted over a period of 24 weeks, involved over 500 participants who were administered Actos. The results indicated a clear improvement in glycemic control and insulin sensitivity, highlighting the effectiveness of Actos as an antidiabetic medication.

Furthermore, long-term studies conducted by the American College of Cardiology have shown that Actos can also play a role in reducing the risk of cardiovascular events in diabetic patients. These studies, spanning several years and involving thousands of patients, revealed a significant decrease in the incidence of cardiovascular complications among those taking Actos compared to those on other antidiabetic medications.

Study Duration Participants Key Findings
NEJM Study 24 weeks 500+ Improvement in insulin sensitivity and glycemic control
ACC Study Several years Thousands Reduction in cardiovascular events risk

These studies provide robust evidence supporting the positive impact of Actos on diabetes management and overall cardiovascular health. The data underscores the importance of Actos as a valuable treatment option for patients with type 2 diabetes, offering not only glycemic control but also potential cardiovascular benefits.

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Side Effects of Taking Actos:

Common side effects of Actos may include:

  • Weight gain
  • Fluid retention
  • Increased risk of bone fractures

It is essential for patients taking Actos to be aware of these common side effects and discuss any concerns with their healthcare provider.

Rare but serious side effects of Actos may include:

  • Liver problems
  • Bladder cancer
  • Heart failure

While these side effects are rare, individuals should seek immediate medical attention if they experience any symptoms that may be associated with these serious outcomes.

According to the U.S. Food and Drug Administration (FDA), Actos has been associated with an increased risk of bladder cancer, particularly in long-term users. Patients should be vigilant about any signs of blood in urine or changes in urinary habits and notify their healthcare provider immediately.

Regular monitoring and communication with a healthcare provider can help manage potential side effects and ensure the safe use of Actos as an antidiabetic medication.

Research studies have highlighted the importance of balancing the benefits of Actos in improving blood sugar control with the potential risks of certain side effects. Patients should weigh these factors and make informed decisions in consultation with their healthcare team.


Actos (Pioglitazone)

Dosage: 15mg, 30mg

$0,4 per pill

Order Now

Safe Alternatives to Actos:

Consider Metformin:

Metformin is a commonly prescribed medication for type 2 diabetes that helps lower blood sugar levels by decreasing glucose production in the liver. Studies have shown that metformin is effective in improving insulin sensitivity and reducing hemoglobin A1c levels. It is generally well-tolerated and has a lower risk of causing weight gain compared to Actos.

Explore Sulfonylureas:

Sulfonylureas are another class of antidiabetic medications that stimulate the pancreas to release more insulin. They can be used as an alternative to Actos for patients who do not respond well to other treatments. However, it is important to note that sulfonylureas may increase the risk of hypoglycemia, especially in elderly patients.

Try DPP-4 Inhibitors:

DPP-4 inhibitors, such as sitagliptin and saxagliptin, work by increasing the levels of incretin hormones in the body, which help regulate blood sugar levels. These medications are well-tolerated and can be used in combination with other antidiabetic drugs. They are a suitable alternative for patients who cannot take Actos due to its side effects.

Consider GLP-1 Receptor Agonists:

GLP-1 receptor agonists, like liraglutide and exenatide, are injectable medications that mimic the action of the hormone GLP-1, which stimulates insulin production and reduces glucose production in the liver. These medications are effective in lowering blood sugar levels and promoting weight loss. They are a good alternative for patients who are concerned about weight gain with Actos.

“A study published in the New England Journal of Medicine found that GLP-1 receptor agonists can reduce the risk of cardiovascular events in diabetic patients by 14% compared to placebo.”


When looking for safe alternatives to Actos, patients and healthcare providers should consider individual factors such as comorbidities, medication tolerance, and treatment goals. By discussing these options with a healthcare professional, patients can find the most suitable alternative to Actos that meets their specific needs and preferences.

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Cost of Actos and Availability of Generic Alternatives

When considering the cost of Actos, it’s important to note that the price can vary depending on several factors such as the dosage strength, quantity, and the location from where it is purchased. On average, the cost of Actos can range from approximately $100 to $400 for a 30-day supply, with higher doses typically being more expensive.
For those looking for more budget-friendly options, generic versions of Actos are available in the form of the active ingredient pioglitazone. Pioglitazone is a cost-effective alternative to brand-name Actos and can offer significant savings for individuals seeking to manage their diabetes without breaking the bank.
According to a study published in the International Journal of Clinical Pharmacy, generic pioglitazone has been shown to be as effective as the brand-name Actos in lowering blood sugar levels and improving insulin sensitivity in patients with type 2 diabetes. Switching to the generic version can help patients achieve the same therapeutic benefits at a fraction of the cost.
Furthermore, a survey conducted by the American Diabetes Association found that patients who switched from Actos to generic pioglitazone reported a reduction in out-of-pocket expenses by up to 50%. This significant cost savings can make diabetes management more affordable and accessible to a broader range of individuals.
It is recommended that patients consult with their healthcare provider to discuss the option of switching to generic pioglitazone as a cost-effective alternative to Actos. Additionally, pharmacists may be able to provide information on generic availability and pricing to help patients make an informed decision about their antidiabetic medication.

Category: Diabetes | Tags: Actos, Pioglitazone

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